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October 9-13th,
2005 |
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D3
launches first silicon calibration slide to provide single reference
calibration standard for up to 50 Raman spectrometers |
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Booth No: 66
FACSS 2005
Quebec City, Canada
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D3 is launching
the first silicon calibration standard to provide single reference
calibration standard for up to 50 Raman spectrometers at FACSS 2005.
Unlike any previous standard, Klarite sCAL slides are produced up
to 50 at a time from a single silicon wafer. This means that,
for the first time, organisations running multiple instruments will
be able to synchronise calibration within laboratories and even between
sites, for significant improvements in productivity and traceability.
For laboratories using a single Raman spectrometer, Klarite sCAL provides
a silicon reference mounted on an easy to use standard three-inch
glass microscope slide, each of which is individually numbered for
traceability. Application of these standards will also significantly
enhance instrument qualification and validation (IQ/OQ testing).
For organisations running multiple Raman instruments, Klarite sCAL
can be supplied as a series of slides with reference chips
all cut from a single silicon wafer. Each chip is mounted on
its own slide and numbered sequentially. This unique set of
up to 50 slides acts as a single calibration reference that can be
used to synchronise instruments, even instruments on different sites.
This means that, for the first time research laboratories, pharmaceutical
production facilities and quality control departments have the flexibility
to carry out Raman analysis on two or more instruments in parallel,
with the potential to speed up projects considerably, and with no
loss in accuracy or reliability of results.
Analysis using Raman relies on the precise measurement of the unique
fingerprint spectra produced by compounds and individual chemicals.
Even a very small drift in calibration of the spectrometer can have
significant effect on comparative results. Although most instruments
are supplied with self-calibrating software, a physical reference
standard is also required by most quality assurance systems, for regular
verification.
The use of Raman for analysis in the pharmaceutical and biomedical
industries, and in forensics, homeland security and analytical chemistry,
is on the up following the launch of Klarite, the surface enhanced
Raman spectroscopy substrate, earlier this year (Jan 2005).
The new substrate significantly enhances Raman signals and offers
unparalleled levels of reproducibility, enabling faster, higher accuracy
detection of biological and chemical samples at lower detection limits.
Klarite is compatible with existing Raman instruments, but the SERS
signals that are generated are many orders of magnitude more intense
than traditional Raman signals.
Klarite sCAL is made using silicon of known purity and doping mounted
in a defined crystallographic direction, making it easier to compare
reference spectra to published data. sCAL devices are shipped
clean in sealed packs so that they are ready to use on arrival. |
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